World’s Largest Brain-Wide CRISPR Atlas to Fuel Drug Discovery

8 million cells across hundreds of cell types, revealing how genes shape the brain in health and disease

Organism-scale CRISPR perturbation across 8 million brain cells — Image: Organism-scale CRISPR perturbation across 8 million brain cells

We’ve released the atlas and tools to accelerate discovery:

Download the full atlas on Hugging Face
Explore the atlas with NVIDIA AI Blueprint for Single-Cell Analysis powered by RAPIDS-singlecell for near-real-time analysis
Read the preprint: Genome-scale Functional Mapping of the Mammalian Whole Brain with in vivo Perturb-seq
Learn how we turn causal in vivo biology into better drug discovery decisions: From whole brain CRISPR atlas to high confidence therapeutic targets